The wash out speed generally depends on the dissociation constant of the compound and the ability of the perfusion system to assure zero compound concentration at the cell surface during wash out. Our perfusion system is able to generate a continuous laminar buffer flow, which assures that the drug concentration at the cell is effectively zeroed during wash-out. Moreover, there is no limit in the possible wash out time, so that even very "sticky" compounds can be 100% washed off. For more details please download our study.
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