As the developer of all system components, we have many years of successful experience in operating the CytoPatch™ Instrument in our lab as a customer screening service. We are aware that the software must be easy to use and flexible enough to fulfil many and varied requirements in order to facilitate your daily work.
The Workflow Manager (WMF) and the CytoPatch™ Software (CPS) guarantee an efficient workflow and will meet your expectations:
The CytoPatch™ Software consists of two main components. First, the central Workflow Manager (WFM) is used to plan, edit and schedule patch clamp studies and furthermore to collect, analyse and archive the data. Second, the CytoPatch™ Software (CPS) runs on each independent CytoPatch™ Instrument and is used to start assays and monitor the recordings.
In the WFM, the compounds and concentrations to be tested and the assay to be used are defined as jobs which are then directed to the individual CytoPatch™ Instrument(s). After receiving the jobs, the CPS controls the respective and entirely automated patch clamp processes running on a single CytoPatch™ Instrument: Chip filling, application of the cells as well as the sealing process, and the establishing of the whole cell configuration are executed automatically. Compensation of electrical capacitances and the serial resistance are accomplished by the CPS controlled patch clamp amplifiers. Test compounds are applied to the cell as defined in the study designed with the WFM software. Raw data and assay results are written to local hard disks and are accessed by the WFM for further analysis and data archiving.
The CPS in turn is installed on each CytoPatch™ Instrument and is used to control the start of the scheduled jobs and also allows monitoring the recordings in real-time.
The Workflow Manager and the CytoPatch™ Software fulfil the requirements of the FDA Regulation 21 CFR 11 with respect to data security, access restriction, audit trail and hardware verification.
Cytocentrics Bioscience GmbH
Joachim - Jungius - Str.9
Germany - 18059 Rostock
Phone: +49(0)381 440 388-0
Fax: +49 (0) 381 440 388-47
E-Mail: info@cytocentrics.com