CytoPatch™:automated whole-cell patch clamp

Successful gigaseal formation. Applicable to voltage- and ligand-gated ion channels

The patch clamp technique is the gold standard for functional investigations of ion channels. Cytocentrics fully automates this technique with the CytoPatch™ instrument. The instrument allows high quality whole-cell patch clamp recordings and reliable data collection through true gigaseal formation. The instrument runs in routine operation in-house and generates precise data similar to manually obtained patch clamp data.

Automated patch clamp gives the highest information content for ion channels. The CytoPatch™ instrument accelerates testing of compounds in drug development and safety screening and is suited for the testing of compounds on ion channel function.

True gigaseals

• Applicable to voltage- and ligand-gated ion channels
• Superior rapid perfusion system for evaluation of fast acting ligand-gated ion channels
• Assay control and multiple compound applications on each cell
• Use of standard microplates
• Small volume consumption
• Rs compensation
• Easy-to-understand software with flexible and complex assay definitions
• Time and cost savings by “BatchSize One”: Intelligent parallel system with independently operating modules.

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